INTRODUCTION

Thalassemia, a hereditary blood disorder characterized by abnormal hemoglobin production, presents significant health challenges in various regions worldwide, including Cambodia. This genetic condition leads to the destruction of red blood cells, causing anemia and other severe complications. In Cambodia, thalassemia affects thousands of people annually, with a significant number of cases identified in younger populations. Awareness and understanding of thalassemia in Cambodia have gradually increased over the past decade thanks to efforts by health organizations, government initiatives, and international collaborations. However, despite these efforts, the management and treatment of thalassemia face significant obstacles. Severe thalassemia diseases are a major health problem in Southeast Asia.

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